| Date | Score | Score | ||||
| 2025-01-08 | Linsly (WV) | 61 | Wheeling Central ** | 71 | ||
| 2025-01-09 | Oak Glen | 61 | Madonna ** | 64 | ||
| 2025-01-09 | University | 69 | Fort Hill (MD) ** | 46 | ||
| 2025-01-09 | Summit Christian (WV) | 65 | Greater Beckley Christian ** | 60 | ||
| 2025-01-10 | Tucker County | 53 | East Hardy ** | 42 | ||
| 2025-01-10 | Williamstown | 64 | Tug Valley ** | 77 | ||
| 2025-01-10 | Keyser | 37 | Hampshire ** | 44 | ||
| 2025-01-10 | Hedgesville | 36 | Martinsburg ** | 39 | ||
| 2025-01-10 | Musselman | 33 | Spring Mills ** | 74 | ||
| 2025-01-10 | Summit Christian (WV) | 53 | Shady Spring ** | 64 | ||
| 2025-01-10 | West Logan Christian (WV) | 33 | Logan ** | 92 | ||
| 2025-01-11 | Williamstown | 57 | Logan ** | 64 |