| Date | H/A | W/L | Team | Score | Opponent | Score | |
| 2008-08-29 | A | L | Bishop Donahue | 12 | Cameron (4) | 19 | 1080 |
| 2008-09-05 | H | L | Bishop Donahue | 8 | Clay-Battelle (8) | 19 | 868 |
| 2008-09-12 | A | L | Bishop Donahue | 7 | Beallsville (OH) (9) | 49 | 1320 |
| 2008-09-19 | H | L | Bishop Donahue | 26 | Bellaire St.John (OH) (3) | 27 | 869 |
| 2008-10-03 | A | W | Bishop Donahue | 47 | Hundred (2) | 6 | 1122 |
| 2008-10-10 | H | W | Bishop Donahue | 20 | Doddridge County (1) | 13 | 870 |
| 2008-10-18 | H | W | Bishop Donahue | 45 | Notre Dame (4) | 28 | 871 |
| 2008-10-24 | A | W | Bishop Donahue | 26 | Valley-Wetzel (1) | 20 | 2 OT1227 |
| 2008-10-30 | H | L | Bishop Donahue | 0 | Madonna (10) | 43 | 872 |
| 2008-11-07 | A | L | Bishop Donahue | 6 | Paden City (5) | 20 | 1178 |