| Date |
|
Score |
|
Score |
|
|
| 2008-09-11 | Langley (PA) ** | 34 | Peabody (PA) | 32 | | |
| 2008-09-12 | Big Creek | 54 | Mt. View ** | 18 | | |
| 2008-09-12 | Calhoun County ** | 41 | Doddridge County | 14 | | |
| 2008-09-12 | Clay-Battelle ** | 27 | Paden City | 6 | | |
| 2008-09-12 | Fayetteville | 70 | Richwood ** | 7 | | |
| 2008-09-12 | Gilbert | 48 | Tug Valley ** | 32 | | |
| 2008-09-12 | Hundred ** | 42 | Valley-Wetzel | 13 | | |
| 2008-09-12 | Man ** | 28 | Westside | 20 | | |
| 2008-09-12 | Matewan ** | 50 | Grundy (VA) | 22 | | |
| 2008-09-12 | Midland Trail | 44 | Meadow Bridge ** | 24 | | |
| 2008-09-12 | Mt. Hope ** | 36 | Iaeger | 14 | | |
| 2008-09-12 | Pocahontas County | 47 | Pendleton County ** | 0 | | |
| 2008-09-12 | South Harrison | 37 | Tygarts Valley ** | 0 | | |
| 2008-09-12 | Tucker County | 34 | Lincoln ** | 13 | | |
| 2008-09-12 | Valley-Fayette | 40 | Van ** | 32 | | |
| 2008-09-12 | Wahama ** | 41 | South Gallia (OH) | 6 | | |
| 2008-09-12 | Wirt County | 28 | Gilmer County ** | 14 | | |
| 2008-09-12 | Chapmanville | 16 | Scott ** | 7 | | |
| 2008-09-12 | Grafton ** | 23 | Frankfort | 14 | | |
| 2008-09-12 | Greenbrier West | 14 | Independence ** | 7 | | |
| 2008-09-12 | James Monroe | 34 | Oak Hill ** | 30 | | |
| 2008-09-12 | Keyser ** | 13 | Fort Hill (MD) | 7 | | |
| 2008-09-12 | Liberty-Raleigh | 20 | PikeView ** | 15 | | |
| 2008-09-12 | Magnolia ** | 27 | Tyler Consolidated | 7 | | |
| 2008-09-12 | Philip Barbour ** | 20 | Braxton County | 13 | | |
| 2008-09-12 | Ravenswood | 26 | Roane County ** | 14 | | |
| 2008-09-12 | Ritchie County ** | 34 | Clay County | 6 | | |
| 2008-09-12 | Shady Spring | 6 | Summers County ** | 0 | | |
| 2008-09-12 | Tolsia ** | 21 | Fairland (OH) | 14 | | |
| 2008-09-12 | Wayne ** | 51 | Herbert Hoover | 24 | | |
| 2008-09-12 | Webster County | 33 | Liberty-Harrison ** | 13 | | |
| 2008-09-12 | Weir ** | 13 | Oak Glen | 12 | | |
| 2008-09-12 | Bridgeport | 26 | Lewis County ** | 7 | | |
| 2008-09-12 | Brooke ** | 34 | John Marshall | 8 | | |
| 2008-09-12 | Cabell Midland ** | 26 | Woodrow Wilson | 0 | | |
| 2008-09-12 | Capital ** | 36 | Huntington | 12 | | |
| 2008-09-12 | East Fairmont ** | 21 | Nicholas County | 13 | | |
| 2008-09-12 | George Washington | 35 | Nitro ** | 6 | | |
| 2008-09-12 | Hurricane ** | 42 | Ripley | 10 | | |
| 2008-09-12 | Lincoln County | 34 | Sissonville ** | 22 | | |
| 2008-09-12 | Logan | 20 | Poca ** | 17 | | |
| 2008-09-12 | Morgantown ** | 42 | Fairmont Sr. | 23 | | |
| 2008-09-12 | Musselman | 34 | Woodstock Central (VA) ** | 6 | | |
| 2008-09-12 | Parkersburg South ** | 48 | Spingarn (DC) | 28 | | |
| 2008-09-12 | Preston | 31 | Elkins ** | 19 | | |
| 2008-09-12 | Princeton ** | 41 | St. Albans | 14 | | |
| 2008-09-12 | Riverside ** | 34 | Winfield | 22 | | |
| 2008-09-12 | Robert C. Byrd | 38 | North Marion ** | 7 | | |
| 2008-09-12 | South Charleston ** | 39 | Parkersburg | 7 | | |
| 2008-09-12 | Spring Valley | 34 | Greenbrier East ** | 6 | | |
| 2008-09-12 | University | 35 | Buckhannon-Upshur ** | 13 | | |
| 2008-09-12 | Wheeling Park ** | 45 | Buckeye Local (OH) | 20 | | |
| 2008-09-12 | Calvin Coolidge (DC) ** | 53 | McKinley (DC) | 0 | | |
| 2008-09-12 | Cardozo (DC) | 14 | Anacostia (DC) ** | 8 | | |
| 2008-09-12 | Pike Central (KY) ** | 40 | Mcgoffin County (KY) | 18 | | |
| 2008-09-12 | Pikeville (KY) ** | 68 | Betsy Layne (KY) | 0 | | |
| 2008-09-12 | Shelby Valley (KY) | 46 | Knott County Central (KY) ** | 14 | | |
| 2008-09-12 | Allegany (MD) ** | 16 | North Hagerstown (MD) | 13 | | |
| 2008-09-12 | Boonsboro (MD) ** | 40 | Southern Garrett County (MD) | 0 | | |
| 2008-09-12 | Mt. Ridge (MD) ** | 42 | Catoctin (MD) | 16 | | |
| 2008-09-12 | Northern Garrett County (MD) ** | 33 | Williamsport (MD) | 0 | | |
| 2008-09-12 | South Hagerstown (MD) ** | 6 | Berkeley Springs | 0 | | |
| 2008-09-12 | St. James (MD) | 21 | Hancock (MD) ** | 0 | | |
| 2008-09-12 | Urbana (MD) | 29 | Martinsburg ** | 28 | | |
| 2008-09-12 | Barnesville (OH) ** | 18 | Buckeye Trail (OH) | 13 | | |
| 2008-09-12 | Beallsville (OH) ** | 49 | Bishop Donahue | 7 | | |
| 2008-09-12 | Bellaire (OH) | 22 | St. Clairsville (OH) ** | 14 | | |
| 2008-09-12 | Chillicothe (OH) | 24 | Zanesville (OH) ** | 21 | | |
| 2008-09-12 | Columbiana (OH) | 42 | Columbiana Crestview (OH) ** | 36 | | |
| 2008-09-12 | Elyria Catholic (OH) ** | 35 | Warren JFK (OH) | 30 | | |
| 2008-09-12 | Frontier (OH) ** | 28 | Miller (OH) | 8 | | |
| 2008-09-12 | Grove City Christian (OH) ** | 27 | Green (OH) | 6 | | |
| 2008-09-12 | John Adams (OH) ** | 28 | East Cleveland (OH) | 7 | | |
| 2008-09-12 | Logan (OH) ** | 40 | Gallia Academy (OH) | 7 | | |
| 2008-09-12 | Marietta (OH) ** | 26 | Warren Local (OH) | 21 | | |
| 2008-09-12 | Martins Ferry (OH) ** | 53 | Linsly (WV) | 7 | | |
| 2008-09-12 | Meigs (OH) ** | 26 | Athens (OH) | 13 | | |
| 2008-09-12 | Monroe Central (OH) ** | 27 | Caldwell (OH) | 14 | | |
| 2008-09-12 | New Lexington (OH) | 68 | Morgan (OH) ** | 7 | | |
| 2008-09-12 | New Philadelphia (OH) ** | 54 | Claymont (OH) | 0 | | |
| 2008-09-12 | Racine Southern (OH) | 57 | Hannan ** | 0 | | |
| 2008-09-12 | River (OH) | 40 | Toronto (OH) ** | 7 | | |
| 2008-09-12 | River Valley Cheshire (OH) | 14 | Reedsville Eastern (OH) ** | 0 | | |
| 2008-09-12 | Sciotoville Community (OH) | 13 | Buffalo ** | 12 | | |
| 2008-09-12 | Shadyside (OH) ** | 22 | Wheeling Central | 14 | | |
| 2008-09-12 | South Point (OH) | 34 | Pt. Pleasant ** | 26 | | |
| 2008-09-12 | Steubenville (OH) ** | 43 | St. Joseph's CI (NY) | 14 | | |
| 2008-09-12 | Symmes Valley (OH) ** | 53 | Manchester (OH) | 30 | | |
| 2008-09-12 | Union Local (OH) ** | 33 | Indian Creek (OH) | 21 | | |
| 2008-09-12 | Valley (OH) | 9 | Chesapeake (OH) ** | 0 | | |
| 2008-09-12 | Brashear (PA) ** | 36 | Schenley (PA) | 12 | | |
| 2008-09-12 | Greencastle Atrium (PA) | 17 | Shippensburg (PA) ** | 0 | | |
| 2008-09-12 | Oliver (PA) | 20 | Allderdice (PA) ** | 0 | | |
| 2008-09-12 | State College (PA) ** | 27 | Central Dauphin (PA) | 13 | | |
| 2008-09-12 | West Greene (TN) ** | 34 | Unaka (TN) | 0 | | |
| 2008-09-12 | Auburn (VA) ** | 21 | Galax (VA) | 6 | | |
| 2008-09-12 | Bath County (VA) | 33 | Petersburg ** | 8 | | |
| 2008-09-12 | Briar Woods (VA) | 28 | Manassas Park (VA) ** | 0 | | |
| 2008-09-12 | Castlewood (VA) | 42 | Twin Valley (VA) ** | 7 | | |
| 2008-09-12 | Covenant (VA) ** | 70 | Kettle Run (VA) | 0 | | |
| 2008-09-12 | Eastern Montgomery (VA) | 38 | Craig County (VA) ** | 0 | | |
| 2008-09-12 | Eastern View (VA) ** | 28 | Monroe (VA) | 21 | | |
| 2008-09-12 | Giles (VA) | 31 | Narrows (VA) ** | 6 | | |
| 2008-09-12 | Graham (VA) | 28 | Marion (VA) ** | 13 | | |
| 2008-09-12 | Holston (VA) | 35 | Bland (VA) ** | 19 | | |
| 2008-09-12 | Hurley (VA) ** | 54 | Burch | 16 | | |
| 2008-09-12 | Loudoun County (VA) | 23 | James Wood (VA) ** | 20 | | |
| 2008-09-12 | Potomac Falls (VA) ** | 31 | Jefferson | 14 | | |
| 2008-09-12 | Richlands (VA) | 27 | Abingdon (VA) ** | 13 | | |
| 2008-09-12 | Sherando (VA) ** | 49 | Hedgesville | 0 | | |
| 2008-09-12 | Turner Ashby (VA) | 21 | Spotswood (VA) ** | 0 | | |
| 2008-09-13 | Madonna | 62 | Bellaire St.John (OH) ** | 14 | | |
| 2008-09-13 | Notre Dame ** | 28 | Cameron | 24 | | |
| 2008-09-13 | St. Marys | 42 | Parkersburg Catholic ** | 14 | | |
| 2008-09-13 | Williamson | 21 | Montcalm ** | 0 | | |
| 2008-09-13 | Wyoming East | 26 | Sherman ** | 12 | | |
| 2008-09-13 | Our Lady of Good Counsel (MD) ** | 42 | Friendship Collegiate (DC) | 0 | | |
| 2008-09-13 | Bridgeport (OH) | 21 | Bishop Rosecrans (OH) ** | 0 | | |
| 2008-09-13 | Chaney (OH) ** | 14 | East Liverpool (OH) | 0 | | |
| 2008-09-13 | Steubenville Central (OH) ** | 20 | Edison Local (OH) | 17 | | |
| 2008-09-13 | McCallie (TN) ** | 19 | Charlotte Country Day Sch (NC) | 11 | | |
| 2008-09-13 | Park View-Sterling (VA) | 17 | Handley (VA) ** | 14 | | |
| 2008-09-13 | Roanoke Catholic (VA) | 34 | Rappahannock County (VA) ** | 6 | | |