| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 0000-00-00 | H | St. Marys | Ravenswood (1) | |||||
| 0000-00-00 | A | St. Marys | Barnesville (OH) (4) | |||||
| 0000-00-00 | A | St. Marys | Tyler Consolidated (2) | |||||
| 2020-09-04 | H | W | St. Marys | 42 | Alexander (OH) (1) | 6 | ||
| 2020-09-11 | H | W | St. Marys | 33 | Grafton (1) | 6 | ||
| 2020-09-18 | H | W | St. Marys | 34 | Ritchie County (10) | 26 | ||
| 2020-09-25 | H | W | St. Marys | 60 | Calhoun County (0) | 8 | ||
| 2020-10-02 | A | L | St. Marys | 7 | Williamstown (5) | 20 | ||
| 2020-10-09 | H | W | St. Marys | 26 | Wirt County (5) | 7 | ||
| 2020-10-16 | A | W | St. Marys | 41 | Magnolia (2) | 7 | ||
| 2020-10-23 | A | W | St. Marys | 54 | South Harrison (4) | 6 | ||
| 2020-10-30 | H | W | St. Marys | 55 | Frontier (OH) (4) | 20 | ||
| 2020-11-15 | H | W | St. Marys | 1 | Wheeling Central (6) | 0 | ||
| 2020-11-22 | H | W | St. Marys | 52 | Midland Trail (5) | 49 | ||
| 2020-11-28 | H | W | St. Marys | 21 | Pendleton County (7) | 7 | ||
| 2020-12-05 | H | W | St. Marys | 1 | Ritchie County (10) | 0 | A State Championship OT |