| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2020-08-29 | A | L | River (OH) | 14 | Bellaire (OH) (2) | 28 | ||
| 2020-09-05 | A | W | River (OH) | 42 | Steubenville Central (OH) (0) | 14 | ||
| 2020-09-11 | A | W | River (OH) | 28 | Monroe Central (OH) (3) | 6 | ||
| 2020-09-18 | H | W | River (OH) | 47 | Magnolia (2) | 14 | ||
| 2020-09-25 | H | W | River (OH) | 27 | Barnesville (OH) (4) | 0 | ||
| 2020-10-02 | H | L | River (OH) | 25 | Shadyside (OH) (3) | 27 |