| Date |
|
Score |
|
Score |
|
|
| 2024-09-26 | Preston ** | 48 | East Fairmont | 20 | | |
| 2024-09-26 | Allegany (MD) | 26 | Albert Gallatin (PA) ** | 14 | | |
| 2024-09-26 | Alleghany Highlands (VA) ** | 27 | Radford (VA) | 9 | | |
| 2024-09-26 | Lord Botetourt (VA) ** | 72 | Rocktown (VA) | 0 | | |
| 2024-09-26 | Page County (VA) | 27 | Mountain View (VA) ** | 12 | | |
| 2024-09-26 | Strasburg (VA) | 28 | King William (VA) ** | 17 | | |
| 2024-09-27 | Cameron | 13 | Tyler Consolidated ** | 6 | | |
| 2024-09-27 | Doddridge County | 35 | Ritchie County ** | 14 | | |
| 2024-09-27 | East Hardy | 36 | Southern Garrett County (MD) ** | 6 | | |
| 2024-09-27 | Greenbrier West ** | 19 | Man | 12 | | |
| 2024-09-27 | Tolsia | 47 | Calhoun County ** | 0 | | |
| 2024-09-27 | Tucker County | 50 | Webster County ** | 0 | | |
| 2024-09-27 | Tygarts Valley | 13 | Clay-Battelle ** | 12 | | |
| 2024-09-27 | Valley-Wetzel ** | 47 | Beallsville (OH) | 0 | | |
| 2024-09-27 | Wahama ** | 68 | Wirt County | 22 | | |
| 2024-09-27 | Frankfort ** | 45 | Northern Garrett County (MD) | 14 | | |
| 2024-09-27 | Liberty-Harrison ** | 42 | Grafton | 27 | | |
| 2024-09-27 | Midland Trail ** | 46 | Summers County | 20 | | |
| 2024-09-27 | Moorefield ** | 47 | Petersburg | 14 | | |
| 2024-09-27 | Roane County ** | 43 | Braxton County | 8 | | |
| 2024-09-27 | Scott ** | 41 | Chapmanville Regional | 6 | | |
| 2024-09-27 | South Harrison ** | 36 | Clay County | 15 | | |
| 2024-09-27 | Wheeling Central ** | 41 | Perry Traditional Acad. (PA) | 12 | | |
| 2024-09-27 | Williamstown ** | 48 | Poca | 0 | | |
| 2024-09-27 | Bridgeport ** | 58 | Robert C. Byrd | 0 | | |
| 2024-09-27 | Brooke | 33 | Lincoln County ** | 14 | | |
| 2024-09-27 | Elkins ** | 21 | Philip Barbour | 14 | 2 OT | |
| 2024-09-27 | Fairmont Sr. ** | 49 | University | 7 | | |
| 2024-09-27 | Herbert Hoover ** | 63 | Sissonville | 19 | | |
| 2024-09-27 | Keyser ** | 21 | Hampshire | 13 | | |
| 2024-09-27 | Nitro ** | 52 | Wayne | 6 | | |
| 2024-09-27 | North Marion ** | 40 | Lincoln | 7 | | |
| 2024-09-27 | Riverside ** | 56 | South Charleston | 20 | | |
| 2024-09-27 | Spring Valley ** | 28 | George Washington | 18 | | |
| 2024-09-27 | Winfield ** | 47 | Logan | 6 | | |
| 2024-09-27 | Hurricane ** | 48 | Cabell Midland | 7 | | |
| 2024-09-27 | Martinsburg | 42 | Jefferson ** | 12 | | |
| 2024-09-27 | Morgantown ** | 49 | Buckhannon-Upshur | 6 | | |
| 2024-09-27 | Parkersburg | 31 | Capital ** | 19 | | |
| 2024-09-27 | Parkersburg South | 41 | John Marshall ** | 12 | | |
| 2024-09-27 | Spring Mills | 64 | North Hagerstown (MD) ** | 0 | | |
| 2024-09-27 | Washington | 42 | Hedgesville ** | 7 | | |
| 2024-09-27 | Clarkson North (CN) | 28 | Ironton (OH) ** | 27 | | |
| 2024-09-27 | Woodson (DC) ** | 20 | Ballou (DC) | 0 | | |
| 2024-09-27 | Frederick (MD) ** | 28 | Mt. Ridge (MD) | 23 | | |
| 2024-09-27 | Hancock (MD) | 49 | Hundred ** | 20 | | |
| 2024-09-27 | Liberty (MD) ** | 21 | Key (MD) | 0 | | |
| 2024-09-27 | Magruder (MD) ** | 13 | Clarksburg (MD) | 9 | | |
| 2024-09-27 | St. James (MD) | 16 | South Hagerstown (MD) ** | 0 | | |
| 2024-09-27 | Thomas Johnson (MD) ** | 41 | Whitman (MD) | 0 | | |
| 2024-09-27 | Williamsport (MD) | 19 | Clear Spring (MD) ** | 7 | | |
| 2024-09-27 | DeWitt (MI) | 42 | East Lansing (MI) ** | 35 | | |
| 2024-09-27 | Bloom-Carroll (OH) | 35 | Fairfield Union (OH) ** | 0 | | |
| 2024-09-27 | Caldwell (OH) ** | 34 | Fort Frye (OH) | 27 | | |
| 2024-09-27 | Conotton Valley (OH) ** | 26 | Buckeye Trail (OH) | 24 | | |
| 2024-09-27 | East Liverpool (OH) | 41 | Cambridge (OH) ** | 7 | | |
| 2024-09-27 | Edison Local (OH) | 35 | Toronto (OH) ** | 19 | | |
| 2024-09-27 | Fairland (OH) ** | 36 | South Point (OH) | 0 | | |
| 2024-09-27 | Frontier (OH) | 48 | Federal Hocking (OH) ** | 16 | | |
| 2024-09-27 | Marietta (OH) ** | 21 | Circleville (OH) | 17 | | |
| 2024-09-27 | Monroe Central (OH) ** | 46 | Magnolia | 0 | | |
| 2024-09-27 | New Philadelphia (OH) | 59 | Linsly (WV) ** | 28 | | |
| 2024-09-27 | River (OH) | 48 | Bridgeport (OH) ** | 6 | | |
| 2024-09-27 | Steubenville (OH) | 48 | Wheeling Park ** | 17 | | |
| 2024-09-27 | Trimble (OH) | 35 | Racine Southern (OH) ** | 13 | | |
| 2024-09-27 | Union Local (OH) | 41 | Beaver Local (OH) ** | 14 | | |
| 2024-09-27 | Valley Christian (OH) | 46 | Wellsville (OH) ** | 14 | | |
| 2024-09-27 | Waterford (OH) ** | 22 | Reedsville Eastern (OH) | 19 | | |
| 2024-09-27 | Butler (PA) | 31 | Connellsville (PA) ** | 0 | | |
| 2024-09-27 | Windber (PA) ** | 49 | Carrick (PA) | 0 | | |
| 2024-09-27 | Loudoun County (VA) ** | 17 | Loudoun Valley (VA) | 14 | | |
| 2024-09-27 | Sherando (VA) | 58 | Liberty Bealton (VA) ** | 7 | | |
| 2024-09-28 | Pocahontas County | 47 | Richwood ** | 6 | | |
| 2024-09-28 | River View ** | 54 | Van | 14 | | |
| 2024-09-28 | Tug Valley | 48 | Morgan County (KY) ** | 6 | | |
| 2024-09-28 | Liberty-Raleigh ** | 48 | Buffalo | 6 | | |
| 2024-09-28 | Berkeley Springs | 27 | Oak Glen ** | 12 | | |
| 2024-09-28 | Princeton ** | 70 | Tazewell (VA) | 13 | | |
| 2024-09-28 | Shady Spring ** | 41 | PikeView | 7 | | |
| 2024-09-28 | Maret (DC) | 42 | Ron Brown Prep (DC) ** | 6 | | |
| 2024-09-28 | East Ridge (KY) ** | 50 | Jenkins (KY) | 6 | | |
| 2024-09-28 | Powell County (KY) | 59 | Fairview (KY) ** | 18 | | |
| 2024-09-28 | Athens (OH) | 27 | Warren Local (OH) ** | 14 | | |
| 2024-09-28 | Dawson-Bryant (OH) ** | 46 | Gallia Academy (OH) | 8 | | |
| 2024-09-28 | Indian Creek (OH) | 40 | Bellaire (OH) ** | 26 | | |
| 2024-09-28 | Richmond Heights (OH) | 34 | Foxfire (OH) ** | 0 | | |
| 2024-09-28 | Steubenville Central (OH) ** | 48 | Madonna | 0 | | |
| 2024-09-28 | Talawanda (OH) ** | 42 | Shroder (OH) | 0 | | |
| 2024-09-28 | Sharon Penn (PA) | 41 | Meadville (PA) ** | 21 | | |
| 2024-09-28 | Christiansburg (VA) ** | 26 | Pulaski County (VA) | 6 | | |
| 2024-09-28 | Graham (VA) | 27 | Virginia (VA) ** | 14 | | |
| 2024-09-28 | Grundy (VA) ** | 42 | Honaker (VA) | 8 | | |
| 2024-09-28 | Handley (VA) ** | 57 | James Wood (VA) | 16 | | |
| 2024-09-28 | Holston (VA) | 48 | Hurley (VA) ** | 24 | | |