| Date | H/A | W/L | Team | Score | Opponent | Score | |||
| 2021-03-06 | A | L | Nicholas County | 66 | Westside | 85 | 654 | ||
| 2021-03-09 | A | L | Nicholas County | 58 | Independence | 86 | 208 | ||
| 2021-03-26 | H | L | Nicholas County | 69 | Westside | 75 | 657 | ||
| 2021-03-27 | A | L | Nicholas County | 55 | Herbert Hoover | 85 | 185 | ||
| 2021-03-29 | A | L | Nicholas County | 75 | Greenbrier West | 87 | 1 OT | 1079 | |
| 2021-03-31 | H | L | Nicholas County | 63 | PikeView | 97 | 632 | ||
| 2021-04-01 | A | L | Nicholas County | 36 | Oak Hill | 63 | 681 | ||
| 2021-04-05 | A | W | Nicholas County | 74 | Sissonville | 60 | 680 | ||
| 2021-04-06 | H | L | Nicholas County | 50 | PikeView | 81 | 1106 | ||
| 2021-04-08 | A | L | Nicholas County | 47 | Herbert Hoover | 86 | 1135 | ||
| 2021-04-09 | H | L | Nicholas County | 63 | Man | 108 | 1105 | ||
| 2021-04-12 | H | W | Nicholas County | 80 | Sissonville | 53 | 1146 | ||
| 2021-04-21 | A | W | Nicholas County | 70 | Midland Trail | 67 | 1180 | ||
| 2021-04-23 | A | L | Nicholas County | 53 | Herbert Hoover | 71 | 1243 | ||
| 2021-04-27 | A | L | Nicholas County | 44 | Shady Spring | 93 | 1269 |