| Date | H/A | W/L | Team | Score | Opponent | Score | |||
| 2021-03-06 | A | L | Wood Co. Christian | 36 | Teays Valley Christian (WV) | 67 | 886 | ||
| 2021-03-08 | H | L | Wood Co. Christian | 33 | Wirt County | 49 | 708 | ||
| 2021-03-11 | A | L | Wood Co. Christian | 27 | Parkersburg Christian (WV) | 33 | 885 | ||
| 2021-03-13 | A | W | Wood Co. Christian | 49 | Ravenswood Heritage Chr. (WV) | 34 | 884 | ||
| 2021-03-16 | A | L | Wood Co. Christian | 39 | Paden City | 48 | 887 | ||
| 2021-03-18 | A | L | Wood Co. Christian | 35 | Clay-Battelle | 71 | 1066 | ||
| 2021-03-20 | H | L | Wood Co. Christian | 48 | Cameron | 71 | 791 | ||
| 2021-03-22 | A | L | Wood Co. Christian | 43 | Wirt County | 56 | 709 | ||
| 2021-03-23 | H | L | Wood Co. Christian | 46 | Paden City | 61 | 883 | ||
| 2021-03-25 | A | W | Wood Co. Christian | 62 | Elk Valley Christian (WV) | 41 | 882 | ||
| 2021-03-30 | H | L | Wood Co. Christian | 45 | Calvary Baptist (WV) | 89 | 881 | ||
| 2021-04-02 | A | L | Wood Co. Christian | 41 | Calvary Baptist (WV) | 86 | 879 | ||
| 2021-04-05 | H | W | Wood Co. Christian | 63 | Hundred | 50 | 1098 | ||
| 2021-04-08 | N | L | Wood Co. Christian | 35 | Calvary Baptist (WV) | 81 | WVCAT 1st RD | 1134 | |
| 2021-04-09 | A | L | Wood Co. Christian | 38 | Cross Lanes Christian (WV) | 45 | 1140 | ||
| 2021-04-12 | H | W | Wood Co. Christian | 57 | Ravenswood Heritage Chr. (WV) | 40 | 878 | ||
| 2021-04-13 | H | L | Wood Co. Christian | 55 | Parkersburg Christian (WV) | 56 | 880 | ||
| 2021-04-16 | H | L | Wood Co. Christian | 24 | Tyler Consolidated | 71 | 877 | ||
| 2021-04-20 | A | L | Wood Co. Christian | 25 | Clay-Battelle | 63 | 1194 |