| Date | H/A | W/L | Team | Score | Opponent | Score | |
| 2008-08-29 | A | W | Buffalo | 22 | Gilbert (4) | 6 | 1105 |
| 2008-09-06 | A | L | Buffalo | 0 | Parkersburg Catholic (6) | 26 | 1179 |
| 2008-09-12 | H | L | Buffalo | 12 | Sciotoville Community (OH) (9) | 13 | 1285 |
| 2008-09-19 | H | L | Buffalo | 12 | Matewan (9) | 37 | 1069 |
| 2008-09-26 | A | W | Buffalo | 40 | South Gallia (OH) (2) | 12 | 1321 |
| 2008-10-03 | H | W | Buffalo | 50 | Notre Dame (4) | 29 | 1070 |
| 2008-10-17 | A | W | Buffalo | 44 | Clay County (0) | 20 | 892 |
| 2008-10-24 | H | L | Buffalo | 20 | Fayetteville (9) | 35 | 1071 |
| 2008-10-31 | A | L | Buffalo | 6 | Man (7) | 14 | 1136 |
| 2008-11-07 | A | W | Buffalo | 38 | Wahama (6) | 19 | 1239 |