| Date | H/A | W/L | Team | Score | Opponent | Score | |
| 2008-08-29 | A | W | Notre Dame | 39 | Hundred (2) | 6 | 1118 |
| 2008-09-05 | A | W | Notre Dame | 18 | Valley-Wetzel (1) | 12 | 1225 |
| 2008-09-13 | H | W | Notre Dame | 28 | Cameron (4) | 24 | 1169 |
| 2008-09-19 | H | L | Notre Dame | 28 | Gilmer County (4) | 32 | 1170 |
| 2008-09-26 | A | L | Notre Dame | 14 | Liberty-Harrison (0) | 39 | 932 |
| 2008-10-03 | A | L | Notre Dame | 29 | Buffalo (5) | 50 | 1070 |
| 2008-10-11 | H | L | Notre Dame | 7 | Madonna (10) | 57 | 1171 |
| 2008-10-18 | A | L | Notre Dame | 28 | Bishop Donahue (4) | 45 | 871 |
| 2008-10-25 | H | W | Notre Dame | 47 | East Hardy (2) | 13 | 1172 |
| 2008-11-01 | H | L | Notre Dame | 12 | Clay-Battelle (8) | 29 | 1173 |