| Date | H/A | W/L | Team | Score | Opponent | Score | |||
| 2021-03-06 | H | L | Valley-Wetzel | 44 | Harman | 63 | 831 | ||
| 2021-03-08 | H | L | Valley-Wetzel | 24 | Clay-Battelle | 61 | 795 | ||
| 2021-03-09 | H | L | Valley-Wetzel | 52 | Paden City | 57 | 920 | ||
| 2021-03-12 | A | L | Valley-Wetzel | 49 | Tyler Consolidated | 74 | 951 | ||
| 2021-03-16 | A | L | Valley-Wetzel | 42 | Madonna | 87 | 871 | ||
| 2021-03-19 | A | W | Valley-Wetzel | 63 | Paden City | 56 | 919 | ||
| 2021-03-25 | H | W | Valley-Wetzel | 69 | Hundred | 48 | 861 | ||
| 2021-03-30 | H | L | Valley-Wetzel | 51 | Tyler Consolidated | 72 | 1095 | ||
| 2021-03-31 | A | L | Valley-Wetzel | 42 | South Harrison | 84 | 937 | ||
| 2021-04-03 | A | L | Valley-Wetzel | 36 | Tygarts Valley | 65 | 950 | ||
| 2021-04-05 | H | L | Valley-Wetzel | 43 | Cameron | 55 | 790 | ||
| 2021-04-06 | H | L | Valley-Wetzel | 47 | Madonna | 68 | 875 | ||
| 2021-04-08 | A | L | Valley-Wetzel | 38 | Clay-Battelle | 73 | 75 | ||
| 2021-04-10 | A | L | Valley-Wetzel | 31 | Magnolia | 78 | 727 | ||
| 2021-04-19 | H | W | Valley-Wetzel | 74 | Hundred | 48 | 1193 | ||
| 2021-04-20 | A | L | Valley-Wetzel | 36 | Cameron | 79 | 1212 |