| Date | H/A | W/L | Team | Score | Opponent | Score | |||
| 2021-03-05 | A | L | South Harrison | 57 | Gilmer County | 63 | 134 | ||
| 2021-03-11 | H | W | South Harrison | 80 | Doddridge County | 56 | 799 | ||
| 2021-03-16 | H | W | South Harrison | 67 | Braxton County | 66 | 777 | ||
| 2021-03-18 | H | L | South Harrison | 62 | Clay County | 67 | 779 | ||
| 2021-03-22 | A | W | South Harrison | 75 | Calhoun County | 23 | 783 | ||
| 2021-03-23 | A | W | South Harrison | 57 | Roane County | 44 | 762 | ||
| 2021-03-30 | H | L | South Harrison | 51 | Gilmer County | 60 | 809 | ||
| 2021-03-31 | H | W | South Harrison | 84 | Valley-Wetzel | 42 | 937 | ||
| 2021-04-01 | H | W | South Harrison | 90 | Calhoun County | 40 | 787 | ||
| 2021-04-06 | A | W | South Harrison | 74 | Doddridge County | 41 | 82 | ||
| 2021-04-08 | H | L | South Harrison | 57 | Ritchie County | 58 | LKC 9th | 1125 | |
| 2021-04-09 | H | W | South Harrison | 69 | Tolsia | 68 | 1 OT | 938 | |
| 2021-04-10 | H | L | South Harrison | 63 | Greenbrier West | 73 | WVHIT D1 Championship | 1144 | |
| 2021-04-20 | H | L | South Harrison | 55 | Braxton County | 59 | 1188 |