| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-27 | A | L | Tazewell (VA) | 14 | Virginia (VA) (1) | 37 | Hx 1105 | |
| 2021-09-03 | A | L | Tazewell (VA) | 6 | Graham (VA) (9) | 34 | Hx 1020 | |
| 2021-09-10 | H | W | Tazewell (VA) | 22 | Mt. View (10) | 18 | Hx 429 | |
| 2021-09-25 | H | L | Tazewell (VA) | 19 | Riverheads (VA) (2) | 56 | Hx 1107 | |
| 2021-10-01 | H | W | Tazewell (VA) | 47 | Grundy (VA) (4) | 14 | Hx 1032 | |
| 2021-10-08 | H | L | Tazewell (VA) | 26 | Richlands (VA) (3) | 27 | Hx 1089 | |
| 2021-10-15 | H | L | Tazewell (VA) | 14 | Bluefield (7) | 57 | Hx 208 | |
| 2021-10-22 | A | W | Tazewell (VA) | 40 | Marion (VA) (0) | 14 | Hx 1108 | |
| 2021-10-29 | A | W | Tazewell (VA) | 34 | Ft. Chiswell (VA) (0) | 28 | 5 OT Hx 1109 | |
| 2021-11-02 | A | W | Tazewell (VA) | 41 | John S. Battle (VA) (0) | 18 | Hx 1106 |