| Date | H/A | W/L | Team | Score | Opponent | Score | |||
| 2021-03-06 | H | W | Liberty-Harrison | 59 | Lewis County | 56 | 505 | ||
| 2021-03-09 | A | L | Liberty-Harrison | 40 | Elkins | 66 | 102 | ||
| 2021-03-11 | A | L | Liberty-Harrison | 41 | Bridgeport | 57 | 516 | ||
| 2021-03-13 | H | L | Liberty-Harrison | 45 | Philip Barbour | 48 | 517 | ||
| 2021-03-16 | A | L | Liberty-Harrison | 52 | Buckhannon-Upshur | 70 | 518 | ||
| 2021-03-20 | A | L | Liberty-Harrison | 46 | Grafton | 71 | 143 | ||
| 2021-03-23 | H | L | Liberty-Harrison | 44 | Lincoln | 63 | 519 | ||
| 2021-03-25 | A | L | Liberty-Harrison | 47 | North Marion | 56 | 468 | ||
| 2021-03-27 | H | L | Liberty-Harrison | 42 | Robert C. Byrd | 75 | 520 | ||
| 2021-03-30 | A | L | Liberty-Harrison | 38 | Robert C. Byrd | 95 | 521 | ||
| 2021-04-01 | A | L | Liberty-Harrison | 59 | Preston | 66 | 522 | ||
| 2021-04-05 | H | L | Liberty-Harrison | 65 | Fairmont Sr. | 92 | 495 | ||
| 2021-04-07 | H | L | Liberty-Harrison | 45 | East Fairmont | 50 | 499 | ||
| 2021-04-09 | H | L | Liberty-Harrison | 30 | Grafton | 60 | 489 | ||
| 2021-04-13 | A | L | Liberty-Harrison | 38 | Lincoln | 66 | 523 | ||
| 2021-04-19 | A | L | Liberty-Harrison | 42 | Lewis County | 57 | 1175 |