| Date | H/A | W/L | Team | Score | Opponent | Score | |||
| 2021-03-06 | A | W | Fairmont Sr. | 61 | Bridgeport | 54 | 490 | ||
| 2021-03-09 | H | W | Fairmont Sr. | 71 | Lewis County | 43 | 110 | ||
| 2021-03-11 | A | W | Fairmont Sr. | 47 | Charleston Catholic | 35 | 1060 | ||
| 2021-03-16 | A | W | Fairmont Sr. | 77 | Elkins | 47 | 103 | ||
| 2021-03-18 | H | W | Fairmont Sr. | 74 | Buckhannon-Upshur | 59 | 112 | ||
| 2021-03-20 | H | W | Fairmont Sr. | 91 | Philip Barbour | 54 | 117 | ||
| 2021-03-23 | A | W | Fairmont Sr. | 67 | Preston | 47 | 493 | ||
| 2021-03-25 | H | W | Fairmont Sr. | 51 | Lincoln | 35 | 113 | ||
| 2021-03-27 | A | W | Fairmont Sr. | 45 | Poca | 38 | 1080 | ||
| 2021-03-30 | H | W | Fairmont Sr. | 78 | Grafton | 51 | 115 | ||
| 2021-04-03 | A | W | Fairmont Sr. | 64 | Notre Dame | 59 | 480 | ||
| 2021-04-05 | A | W | Fairmont Sr. | 92 | Liberty-Harrison | 65 | 495 | ||
| 2021-04-07 | H | W | Fairmont Sr. | 75 | North Marion | 43 | 116 | ||
| 2021-04-09 | A | L | Fairmont Sr. | 55 | Robert C. Byrd | 57 | 496 | ||
| 2021-04-21 | H | W | Fairmont Sr. | 88 | Philip Barbour | 75 | 1209 | ||
| 2021-04-23 | H | W | Fairmont Sr. | 60 | Grafton | 50 | 1239 | ||
| 2021-04-27 | H | W | Fairmont Sr. | 1 | Lincoln | 0 | 1268 | ||
| 2021-05-05 | H | L | Fairmont Sr. | 45 | Winfield | 49 | 1282 |