| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-27 | A | L | River View | 0 | Mt. View (10) | 40 | Hx 582 | |
| 2021-09-10 | H | L | River View | 18 | Sherman (6) | 35 | Hx 1134 | |
| 2021-09-17 | H | W | River View | 30 | Hurley (VA) (2) | 22 | Hx 437 | |
| 2021-09-24 | A | L | River View | 6 | Van (5) | 12 | Hx 615 | |
| 2021-10-08 | H | W | River View | 30 | Twin Valley (VA) (7) | 14 | Hx 438 | |
| 2021-10-12 | H | W | River View | 36 | Wyoming East (1) | 13 | Hx 400 | |
| 2021-10-15 | H | W | River View | 24 | Montcalm (2) | 12 | Hx 576 | |
| 2021-10-22 | H | L | River View | 6 | Clay County (3) | 20 | Hx 237 | |
| 2021-10-29 | A | L | River View | 26 | PikeView (1) | 36 | Hx 355 | |
| 2021-11-05 | A | L | River View | 34 | Richwood (3) | 38 | Hx 609 |