| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-27 | H | L | Pendleton County | 14 | Grafton (5) | 40 | Hx 264 | |
| 2021-09-11 | H | W | Pendleton County | 20 | Petersburg (3) | 13 | Hx 591 | |
| 2021-09-21 | A | L | Pendleton County | 7 | James Monroe (8) | 12 | Hx 536 | |
| 2021-10-01 | A | L | Pendleton County | 0 | Tucker County (2) | 14 | Hx 592 | |
| 2021-10-08 | H | W | Pendleton County | 21 | Tygarts Valley (4) | 14 | Hx 593 | |
| 2021-10-15 | A | L | Pendleton County | 7 | Pocahontas County (5) | 12 | Hx 594 | |
| 2021-10-22 | H | L | Pendleton County | 0 | East Hardy (10) | 39 | Hx 503 | |
| 2021-10-28 | A | L | Pendleton County | 0 | Moorefield (7) | 40 | Hx 581 |