| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-09-03 | A | L | Madison (OH) | 7 | Perry (OH) (3) | 43 | Hx 1224 | |
| 2021-09-10 | H | L | Madison (OH) | 14 | Willoughby South (OH) (4) | 41 | Hx 1241 | |
| 2021-09-17 | H | L | Madison (OH) | 0 | Painesville Riverside (OH) (5) | 45 | Hx 900 | |
| 2021-09-24 | A | L | Madison (OH) | 7 | East Lake North (OH) (1) | 28 | Hx 1245 | |
| 2021-10-01 | H | L | Madison (OH) | 15 | Chagrin Falls Kensten (OH) (4) | 42 | Hx 1244 | |
| 2021-10-08 | A | L | Madison (OH) | 0 | Chardon (OH) (4) | 48 | Hx 1225 | |
| 2021-10-15 | H | L | Madison (OH) | 6 | Cleveland Mayfield (OH) (2) | 21 | Hx 1247 | |
| 2021-10-22 | A | W | Madison (OH) | 22 | Garfield Heights Trinity (OH) (0) | 19 | Hx 1251 |