| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-09-03 | H | W | Willoughby South (OH) | 31 | Maple Heights (OH) (0) | 14 | Hx 1242 | |
| 2021-09-10 | A | W | Willoughby South (OH) | 41 | Madison (OH) (0) | 14 | Hx 1241 | |
| 2021-09-17 | H | W | Willoughby South (OH) | 38 | East Lake North (OH) (1) | 7 | Hx 1240 | |
| 2021-10-01 | H | W | Willoughby South (OH) | 21 | Cleveland Mayfield (OH) (2) | 15 | Hx 1249 | |
| 2021-10-08 | A | L | Willoughby South (OH) | 0 | Chagrin Falls Kensten (OH) (4) | 3 | Hx 1243 | |
| 2021-10-22 | A | L | Willoughby South (OH) | 7 | Painesville Riverside (OH) (5) | 14 | Hx 903 |