| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-27 | A | L | River View | 0 | Mt. View () | 40 | 582 | |
| 2021-09-10 | H | L | River View | 18 | Sherman () | 35 | 1134 | |
| 2021-09-17 | H | W | River View | 30 | Hurley (VA) () | 22 | 437 | |
| 2021-09-24 | A | L | River View | 6 | Van () | 12 | 615 | |
| 2021-10-08 | H | W | River View | 30 | Twin Valley (VA) () | 14 | 438 | |
| 2021-10-12 | H | W | River View | 36 | Wyoming East () | 13 | 400 | |
| 2021-10-15 | H | W | River View | 24 | Montcalm () | 12 | 576 | |
| 2021-10-22 | H | L | River View | 6 | Clay County () | 20 | 237 | |
| 2021-10-29 | A | L | River View | 26 | PikeView () | 36 | 355 | |
| 2021-11-05 | A | L | River View | 34 | Richwood () | 38 | 609 |