| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-27 | H | L | Pendleton County | 14 | Grafton () | 40 | 264 | |
| 2021-09-11 | H | W | Pendleton County | 20 | Petersburg () | 13 | 591 | |
| 2021-09-21 | A | L | Pendleton County | 7 | James Monroe () | 12 | 536 | |
| 2021-10-01 | A | L | Pendleton County | 0 | Tucker County () | 14 | 592 | |
| 2021-10-08 | H | W | Pendleton County | 21 | Tygarts Valley () | 14 | 593 | |
| 2021-10-15 | A | L | Pendleton County | 7 | Pocahontas County () | 12 | 594 | |
| 2021-10-22 | H | L | Pendleton County | 0 | East Hardy () | 39 | 503 | |
| 2021-10-28 | A | L | Pendleton County | 0 | Moorefield () | 40 | 581 |