| Date | H/A | W/L | Team | Score | Opponent | Score | |||
| 2021-03-06 | A | W | Williamstown | 68 | Magnolia | 41 | 719 | ||
| 2021-03-09 | H | W | Williamstown | 77 | Ritchie County | 54 | 696 | ||
| 2021-03-11 | A | W | Williamstown | 71 | St. Marys | 46 | 698 | ||
| 2021-03-16 | A | W | Williamstown | 56 | Ravenswood | 35 | 700 | ||
| 2021-03-17 | N | L | Williamstown | 66 | Greenbrier West | 67 | WV State | 821 | |
| 2021-03-18 | H | W | Williamstown | 79 | Parkersburg Catholic | 25 | 686 | ||
| 2021-03-22 | A | W | Williamstown | 73 | Cameron | 42 | 47 | ||
| 2021-03-23 | A | W | Williamstown | 59 | Wirt County | 33 | 702 | ||
| 2021-03-25 | H | W | Williamstown | 49 | Wahama | 42 | 703 | ||
| 2021-04-05 | A | W | Williamstown | 79 | Tyler Consolidated | 51 | 694 | ||
| 2021-04-06 | H | W | Williamstown | 64 | St. Marys | 41 | 699 | ||
| 2021-04-09 | A | W | Williamstown | 84 | Parkersburg Catholic | 56 | 693 | ||
| 2021-04-12 | N | W | Williamstown | 55 | Clay County | 44 | LKC Championship OT | 1121 | |
| 2021-04-23 | H | W | Williamstown | 76 | Wirt County | 34 | 1228 | ||
| 2021-04-29 | H | W | Williamstown | 70 | St. Marys | 58 | 1274 | ||
| 2021-05-04 | H | W | Williamstown | 67 | Moorefield | 32 | 1294 | ||
| 2021-05-07 | H | W | Williamstown | 55 | Chapmanville Regional | 41 | State Semi | 1301 | |
| 2021-05-08 | H | W | Williamstown | 50 | Poca | 47 | AA State Finals | 1307 |