| Date | H/A | W/L | Team | Score | Opponent | Score | |||
| 2021-03-05 | H | W | Webster County | 78 | Roane County | 54 | 757 | ||
| 2021-03-09 | A | W | Webster County | 71 | Braxton County | 59 | 21 | ||
| 2021-03-22 | A | L | Webster County | 69 | Clay County | 83 | 64 | ||
| 2021-03-23 | A | W | Webster County | 71 | Gilmer County | 64 | 139 | ||
| 2021-03-26 | H | W | Webster County | 97 | Doddridge County | 64 | 801 | ||
| 2021-03-29 | A | L | Webster County | 81 | Roane County | 82 | 3 OT | 763 | |
| 2021-03-31 | N | W | Webster County | 75 | Greenbrier West | 46 | Beckley Armory | 818 | |
| 2021-04-02 | A | L | Webster County | 51 | James Monroe | 61 | 1088 | ||
| 2021-04-05 | H | W | Webster County | 76 | Richwood | 56 | 974 | ||
| 2021-04-06 | H | L | Webster County | 76 | Clay County | 85 | 1 OT | 781 | |
| 2021-04-08 | H | W | Webster County | 71 | Greater Beckley Christian | 59 | 1133 | ||
| 2021-04-12 | N | L | Webster County | 52 | St. Marys | 64 | LKC 3rd | 1122 | |
| 2021-04-15 | A | L | Webster County | 70 | Greater Beckley Christian | 75 | 1 OT | 1137 | |
| 2021-04-20 | H | W | Webster County | 95 | Meadow Bridge | 31 | 1201 | ||
| 2021-04-22 | H | W | Webster County | 64 | Greenbrier West | 57 | 1219 | ||
| 2021-04-28 | H | W | Webster County | 82 | Greater Beckley Christian | 81 | 1 OT | 1261 | |
| 2021-05-04 | H | W | Webster County | 48 | Clay-Battelle | 42 | 1288 | ||
| 2021-05-06 | A | L | Webster County | 54 | Man | 81 | State Semi | 1299 |