| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-09-03 | H | W | Trinity | 28 | Bridgeport (OH) (3) | 14 | Hx 440 | |
| 2021-09-24 | A | W | Trinity | 30 | Racine Southern (OH) (4) | 0 | Hx 442 | |
| 2021-10-01 | H | L | Trinity | 13 | Cameron (9) | 22 | Hx 569 | |
| 2021-10-06 | A | W | Trinity | 1 | Paden City (2) | 0 | Hx 588 | |
| 2021-10-08 | A | W | Trinity | 63 | Hundred (0) | 0 | Hx 1125 | |
| 2021-10-15 | A | W | Trinity | 53 | Hancock (MD) (1) | 0 | Hx 443 | |
| 2021-10-22 | H | W | Trinity | 21 | Tygarts Valley (4) | 14 | Hx 570 | |
| 2021-10-29 | A | L | Trinity | 0 | Cameron (9) | 30 | Hx 485 | |
| 2021-11-05 | H | W | Trinity | 31 | Madonna (6) | 14 | Hx 540 | |
| 2021-11-13 | A | L | Trinity | 0 | James Monroe (8) | 32 | 7-10 1st RD | Hx 1269 |