| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-26 | A | L | Hedgesville | 0 | Washington (5) | 20 | Hx 88 | |
| 2021-09-03 | H | W | Hedgesville | 14 | Warren County (VA) (2) | 12 | Hx 89 | |
| 2021-09-10 | H | W | Hedgesville | 28 | East Fairmont (5) | 0 | Hx 90 | |
| 2021-09-17 | A | L | Hedgesville | 20 | Morgantown (5) | 62 | Hx 91 | |
| 2021-09-24 | H | L | Hedgesville | 6 | Martinsburg (13) | 54 | Hx 92 | |
| 2021-10-01 | A | W | Hedgesville | 20 | Spring Mills (3) | 7 | Hx 93 | |
| 2021-10-08 | H | L | Hedgesville | 0 | Musselman (3) | 35 | Hx 94 | |
| 2021-10-15 | H | L | Hedgesville | 16 | Princeton (4) | 21 | Hx 95 | |
| 2021-10-29 | A | L | Hedgesville | 7 | Jefferson (10) | 43 | Hx 96 | |
| 2021-11-06 | A | W | Hedgesville | 34 | Hampshire (2) | 21 | Hx 87 |