| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-27 | H | L | Spring Mills | 23 | Musselman (3) | 56 | Hx 157 | |
| 2021-09-03 | H | W | Spring Mills | 1 | Washington (5) | 0 | Hx 185 | |
| 2021-09-10 | A | W | Spring Mills | 51 | Hampshire (2) | 7 | Hx 81 | |
| 2021-09-17 | A | L | Spring Mills | 7 | Jefferson (10) | 34 | Hx 111 | |
| 2021-10-01 | H | L | Spring Mills | 7 | Hedgesville (3) | 20 | Hx 93 | |
| 2021-10-08 | H | W | Spring Mills | 21 | Frankfort (6) | 20 | Hx 186 | |
| 2021-10-15 | A | L | Spring Mills | 16 | Martinsburg (13) | 63 | Hx 137 | |
| 2021-10-22 | H | W | Spring Mills | 31 | North Hagerstown (MD) (2) | 6 | Hx 149 | |
| 2021-10-29 | H | L | Spring Mills | 7 | Albert Gallatin (PA) (1) | 15 | Hx 150 | |
| 2021-11-05 | H | L | Spring Mills | 13 | Morgantown (5) | 49 | Hx 144 |