| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-30 | H | L | Elkins | 6 | Liberty-Harrison (4) | 33 | Hx 244 | |
| 2021-09-03 | A | L | Elkins | 0 | Robert C. Byrd (7) | 57 | Hx 245 | |
| 2021-09-10 | A | L | Elkins | 8 | Lewis County (2) | 22 | Hx 246 | |
| 2021-09-24 | A | L | Elkins | 20 | Philip Barbour (1) | 49 | Hx 247 | |
| 2021-10-01 | H | L | Elkins | 13 | Grafton (5) | 46 | Hx 248 | |
| 2021-10-08 | H | L | Elkins | 7 | North Marion (8) | 53 | Hx 249 | |
| 2021-10-15 | A | L | Elkins | 0 | Lincoln (8) | 1 | Hx 250 | |
| 2021-10-22 | A | L | Elkins | 0 | Frankfort (6) | 53 | Hx 251 | |
| 2021-10-29 | A | L | Elkins | 0 | Fairmont Sr. (9) | 53 | Hx 252 | |
| 2021-11-05 | H | L | Elkins | 6 | Buckhannon-Upshur (0) | 33 | Hx 47 |