| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-09-10 | H | W | Caldwell (OH) | 73 | Monroe Central (OH) (4) | 46 | Hx 769 | |
| 2021-09-17 | A | W | Caldwell (OH) | 29 | Reedsville Eastern (OH) (4) | 27 | Hx 785 | |
| 2021-09-24 | H | W | Caldwell (OH) | 21 | Conotton Valley (OH) (5) | 16 | Hx 697 | |
| 2021-10-15 | A | W | Caldwell (OH) | 27 | Waterford (OH) (6) | 14 | Hx 852 |