| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-09-03 | H | W | Philip Barbour | 1 | Petersburg () | 0 | 347 | |
| 2021-09-10 | H | L | Philip Barbour | 16 | Buckhannon-Upshur () | 27 | 40 | |
| 2021-09-17 | A | L | Philip Barbour | 26 | Liberty-Harrison () | 34 | 301 | |
| 2021-09-24 | H | W | Philip Barbour | 49 | Elkins () | 20 | 247 | |
| 2021-10-01 | A | L | Philip Barbour | 12 | Clay County () | 20 | 231 | |
| 2021-10-08 | A | L | Philip Barbour | 24 | East Fairmont () | 64 | 240 | |
| 2021-10-22 | A | L | Philip Barbour | 21 | Lewis County () | 52 | 299 | |
| 2021-10-28 | A | L | Philip Barbour | 0 | Grafton () | 1 | 1258 | |
| 2021-10-29 | H | L | Philip Barbour | 0 | Lincoln () | 56 | 316 | |
| 2021-11-05 | H | L | Philip Barbour | 6 | Robert C. Byrd () | 57 | 348 |