| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-09-03 | H | L | Webster County | 14 | Gilmer County () | 54 | 506 | |
| 2021-09-10 | H | L | Webster County | 14 | Tygarts Valley () | 43 | 627 | |
| 2021-09-17 | A | L | Webster County | 6 | Greenbrier West () | 58 | 515 | |
| 2021-09-21 | H | L | Webster County | 12 | Richwood () | 14 | 605 | |
| 2021-10-08 | A | L | Webster County | 14 | Meadow Bridge () | 42 | 552 | |
| 2021-10-15 | A | L | Webster County | 0 | Ritchie County () | 61 | 614 | |
| 2021-10-22 | A | L | Webster County | 6 | Braxton County () | 47 | 217 | |
| 2021-10-29 | H | W | Webster County | 21 | Paden City () | 12 | 589 | |
| 2021-11-05 | H | W | Webster County | 41 | Montcalm () | 20 | 577 |