| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-20 | H | L | East Liverpool (OH) | 6 | West Branch (OH) (1) | 46 | Hx 700 | |
| 2021-08-27 | H | W | East Liverpool (OH) | 35 | Indian Creek (OH) (0) | 14 | Hx 701 | |
| 2021-09-03 | H | L | East Liverpool (OH) | 20 | Salem (OH) (2) | 42 | Hx 702 | |
| 2021-09-10 | A | L | East Liverpool (OH) | 0 | Beaver Local (OH) (3) | 48 | Hx 683 | |
| 2021-09-24 | H | L | East Liverpool (OH) | 0 | Chardon Notre Dame Latin (OH) (1) | 27 | Hx 890 | |
| 2021-10-01 | H | L | East Liverpool (OH) | 24 | Edison Local (OH) (6) | 34 | Hx 704 | |
| 2021-10-15 | A | W | East Liverpool (OH) | 34 | Oak Glen (2) | 13 | Hx 346 | |
| 2021-10-22 | A | W | East Liverpool (OH) | 41 | Weir (2) | 28 | Hx 376 |