| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-27 | H | W | Lincoln | 49 | Braxton County () | 6 | 211 | |
| 2021-09-10 | A | W | Lincoln | 27 | Grafton () | 7 | 265 | |
| 2021-09-16 | A | W | Lincoln | 21 | Nicholas County () | 13 | 313 | |
| 2021-10-01 | A | W | Lincoln | 21 | Lewis County () | 6 | 297 | |
| 2021-10-08 | A | L | Lincoln | 13 | Robert C. Byrd () | 35 | 315 | |
| 2021-10-15 | H | W | Lincoln | 1 | Elkins () | 0 | 250 | |
| 2021-10-22 | H | W | Lincoln | 34 | Liberty-Harrison () | 14 | 302 | |
| 2021-10-25 | H | W | Lincoln | 1 | North Marion () | 0 | 1253 | |
| 2021-10-29 | A | W | Lincoln | 56 | Philip Barbour () | 0 | 316 | |
| 2021-11-05 | H | L | Lincoln | 7 | Bridgeport () | 38 | 28 | |
| 2021-11-12 | H | L | Lincoln | 17 | Frankfort () | 21 | 4-13 1st RD | 1274 |