| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-27 | A | W | Herbert Hoover | 24 | Scott () | 9 | 271 | |
| 2021-09-03 | A | W | Herbert Hoover | 37 | Winfield () | 14 | 272 | |
| 2021-09-10 | H | W | Herbert Hoover | 48 | Nitro () | 0 | 273 | |
| 2021-09-17 | H | W | Herbert Hoover | 70 | Wyoming East () | 6 | 274 | |
| 2021-09-24 | A | W | Herbert Hoover | 70 | Sissonville () | 0 | 275 | |
| 2021-10-01 | H | W | Herbert Hoover | 55 | Chapmanville Regional () | 7 | 225 | |
| 2021-10-08 | A | W | Herbert Hoover | 53 | Wayne () | 0 | 276 | |
| 2021-10-22 | A | W | Herbert Hoover | 57 | Mingo Central () | 0 | 277 | |
| 2021-10-29 | H | W | Herbert Hoover | 28 | Poca () | 0 | 278 | |
| 2021-11-05 | H | W | Herbert Hoover | 48 | Logan () | 6 | 279 | |
| 2021-11-13 | H | L | Herbert Hoover | 28 | Fairmont Sr. () | 30 | 1-16 1st RD | 1272 |