| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-27 | A | L | Winfield | 10 | Hurricane () | 48 | 103 | |
| 2021-09-03 | H | L | Winfield | 14 | Herbert Hoover () | 37 | 272 | |
| 2021-09-10 | A | W | Winfield | 28 | Chapmanville Regional () | 24 | 222 | |
| 2021-09-17 | H | W | Winfield | 35 | Wayne () | 20 | 392 | |
| 2021-09-24 | A | W | Winfield | 41 | Logan () | 20 | 320 | |
| 2021-10-08 | A | L | Winfield | 26 | Poca () | 28 | 357 | |
| 2021-10-15 | H | W | Winfield | 44 | Sissonville () | 7 | 390 | |
| 2021-10-22 | H | W | Winfield | 34 | Nitro () | 0 | 338 | |
| 2021-10-29 | A | L | Winfield | 10 | Scott () | 28 | 385 | |
| 2021-11-05 | H | L | Winfield | 14 | Pt. Pleasant () | 17 | 363 |