| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-27 | H | W | Shady Spring | 42 | Tug Valley (4) | 0 | Hx 386 | |
| 2021-09-03 | H | L | Shady Spring | 14 | Nicholas County (6) | 38 | Hx 330 | |
| 2021-09-17 | A | L | Shady Spring | 17 | Independence (8) | 50 | Hx 282 | |
| 2021-09-28 | H | W | Shady Spring | 19 | Summers County (2) | 12 | Hx 387 | |
| 2021-10-01 | A | W | Shady Spring | 1 | Westside (1) | 0 | Hx 388 | |
| 2021-10-08 | A | W | Shady Spring | 6 | Wyoming East (1) | 0 | Hx 389 | |
| 2021-10-15 | H | L | Shady Spring | 12 | Mingo Central (2) | 45 | Hx 328 | |
| 2021-10-22 | H | W | Shady Spring | 28 | Ripley (1) | 14 | Hx 176 | |
| 2021-10-29 | A | W | Shady Spring | 29 | Liberty-Raleigh (6) | 26 | Hx 310 | |
| 2021-11-02 | A | W | Shady Spring | 40 | PikeView (1) | 26 | Hx 352 | |
| 2021-11-12 | A | L | Shady Spring | 7 | Independence (8) | 73 | 2-15 1st RD | Hx 1276 |