| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-27 | H | W | Magnolia | 43 | Ravenswood () | 27 | 541 | |
| 2021-09-03 | A | L | Magnolia | 14 | Wirt County () | 27 | 542 | |
| 2021-09-24 | H | L | Magnolia | 19 | Monroe Central (OH) () | 43 | 420 | |
| 2021-10-01 | H | L | Magnolia | 23 | Union Local (OH) () | 26 | 421 | |
| 2021-10-08 | A | L | Magnolia | 21 | Frontier (OH) () | 28 | 422 | |
| 2021-10-15 | A | L | Magnolia | 7 | St. Marys () | 34 | 543 | |
| 2021-10-22 | A | L | Magnolia | 7 | Tyler Consolidated () | 49 | 544 | |
| 2021-10-29 | H | L | Magnolia | 18 | Wahama () | 42 | 1159 | |
| 2021-11-05 | A | L | Magnolia | 6 | Williamstown () | 53 | 545 |