| Date | H/A | W/L | Team | Score | Opponent | Score | ||
| 2021-08-27 | H | W | Shady Spring | 42 | Tug Valley () | 0 | 386 | |
| 2021-09-03 | H | L | Shady Spring | 14 | Nicholas County () | 38 | 330 | |
| 2021-09-17 | A | L | Shady Spring | 17 | Independence () | 50 | 282 | |
| 2021-09-28 | H | W | Shady Spring | 19 | Summers County () | 12 | 387 | |
| 2021-10-01 | A | W | Shady Spring | 1 | Westside () | 0 | 388 | |
| 2021-10-08 | A | W | Shady Spring | 6 | Wyoming East () | 0 | 389 | |
| 2021-10-15 | H | L | Shady Spring | 12 | Mingo Central () | 45 | 328 | |
| 2021-10-22 | H | W | Shady Spring | 28 | Ripley () | 14 | 176 | |
| 2021-10-29 | A | W | Shady Spring | 29 | Liberty-Raleigh () | 26 | 310 | |
| 2021-11-02 | A | W | Shady Spring | 40 | PikeView () | 26 | 352 | |
| 2021-11-12 | A | L | Shady Spring | 7 | Independence () | 73 | 2-15 1st RD | 1276 |